DGKQ antibody

Catalog No. ABIN7113465

This anti-DGKQ antibody is a Rabbit Polyclonal antibody detecting DGKQ in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for DGKQ antibody (ABIN7113465)

Target: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DGKQ Antibody

Purpose: DGKQ antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: diacylglycerol kinase, theta 110kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DGKQ

Target: DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

Alternative Name: DGKQ

Background:

Synonyms: Diacylglycerol kinase theta (DAG kinase theta, DGKtheta)|Diglyceride kinase theta (DGK-theta)|DGKQ|DAGK4

Background: Phosphorylates diacylglycerol(DAG) to generate phosphatidic acid(PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor(By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.

Molecular Weight: 110 kDa

Gene ID: 1609

UniProt: P52824